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A Role for microRNA-155 Modulation in the Anti-HIV-1 Effects of Toll-Like Receptor 3 Stimulation in Macrophages
HIV-1 infection of macrophages plays a key role in viral pathogenesis and progression to AIDS. Polyinosine-polycytidylic acid (poly(I∶C); a synthetic analog of dsRNA) and bacterial lipopolysaccharide (LPS), the ligands for Toll-like receptors (TLR) TLR3 and TLR4, respectively, are known to decrease...
Autores principales: | Swaminathan, Gokul, Rossi, Fiorella, Sierra, Luz-Jeannette, Gupta, Archana, Navas-Martín, Sonia, Martín-García, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447756/ https://www.ncbi.nlm.nih.gov/pubmed/23028330 http://dx.doi.org/10.1371/journal.ppat.1002937 |
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