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Characterization of PTPRG in Knockdown and Phosphatase-Inactive Mutant Mice and Substrate Trapping Analysis of PTPRG in Mammalian Cells

Receptor tyrosine phosphatase gamma (PTPRG, or RPTPγ) is a mammalian receptor-like tyrosine phosphatase which is highly expressed in the nervous system as well as other tissues. Its function and biochemical characteristics remain largely unknown. We created a knockdown (KD) line of this gene in mous...

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Detalles Bibliográficos
Autores principales: Zhang, Wandong, Savelieva, Katerina V., Tran, David T., Pogorelov, Vladimir M., Cullinan, Emily B., Baker, Kevin B., Platt, Kenneth A., Hu, Sean, Rajan, Indrani, Xu, Nianhua, Lanthorn, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447766/
https://www.ncbi.nlm.nih.gov/pubmed/23029056
http://dx.doi.org/10.1371/journal.pone.0045500