Specific Silencing of the REST Target Genes in Insulin-Secreting Cells Uncovers Their Participation in Beta Cell Survival

The absence of the transcriptional repressor RE-1 Silencing Transcription Factor (REST) in insulin-secreting beta cells is a major cue for the specific expression of a large number of genes. These REST target genes were largely ascribed to a function of neurotransmission in a neuronal context, where...

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Detalles Bibliográficos
Autores principales: Martin, David, Allagnat, Florent, Gesina, Emilie, Caille, Dorothee, Gjinovci, Asllan, Waeber, Gerard, Meda, Paolo, Haefliger, Jacques-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447792/
https://www.ncbi.nlm.nih.gov/pubmed/23029270
http://dx.doi.org/10.1371/journal.pone.0045844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447792/
https://www.ncbi.nlm.nih.gov/pubmed/23029270
http://dx.doi.org/10.1371/journal.pone.0045844

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