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Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells
Historically, the analysis of DNA replication in mammalian tissue culture cells has been limited to static time points, and the use of nucleoside analogues to pulse-label replicating DNA. Here we characterize for the first time a novel Chromobody cell line that specifically labels endogenous PCNA. B...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447815/ https://www.ncbi.nlm.nih.gov/pubmed/23029203 http://dx.doi.org/10.1371/journal.pone.0045726 |