Crystal Structures of Human CaMKIα Reveal Insights into the Regulation Mechanism of CaMKI

Human calcium/calmodulin-dependent protein kinase I (CaMKI) plays pivotal roles in the nervous system. The activity of human CaMKI is regulated by a regulatory region including an autoinhibitory segment and a CaM-binding segment. We report here four structures of three CaMKIα truncates in apo form a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zha, Manwu, Zhong, Chen, Ou, Ying, Han, Li, Wang, Jianchuan, Ding, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447817/
https://www.ncbi.nlm.nih.gov/pubmed/23028635
http://dx.doi.org/10.1371/journal.pone.0044828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447817/
https://www.ncbi.nlm.nih.gov/pubmed/23028635
http://dx.doi.org/10.1371/journal.pone.0044828

Ejemplares similares