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Crystal Structures of Human CaMKIα Reveal Insights into the Regulation Mechanism of CaMKI

Human calcium/calmodulin-dependent protein kinase I (CaMKI) plays pivotal roles in the nervous system. The activity of human CaMKI is regulated by a regulatory region including an autoinhibitory segment and a CaM-binding segment. We report here four structures of three CaMKIα truncates in apo form a...

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Detalles Bibliográficos
Autores principales:	Zha, Manwu, Zhong, Chen, Ou, Ying, Han, Li, Wang, Jianchuan, Ding, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447817/ https://www.ncbi.nlm.nih.gov/pubmed/23028635 http://dx.doi.org/10.1371/journal.pone.0044828

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