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Opc Expression, LPS Immunotype Switch and Pilin Conversion Contribute to Serum Resistance of Unencapsulated Meningococci

Neisseria meningitidis employs polysaccharides and outer membrane proteins to cope with human serum complement attack. To screen for factors influencing serum resistance, an assay was developed based on a colorimetric serum bactericidal assay. The screening used a genetically modified sequence type...

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Detalles Bibliográficos
Autores principales: Hubert, Kerstin, Pawlik, Marie-Christin, Claus, Heike, Jarva, Hanna, Meri, Seppo, Vogel, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447861/
https://www.ncbi.nlm.nih.gov/pubmed/23028802
http://dx.doi.org/10.1371/journal.pone.0045132