Identifying the Preferred Subset of Enzymatic Profiles in Nonlinear Kinetic Metabolic Models via Multiobjective Global Optimization and Pareto Filters

Optimization models in metabolic engineering and systems biology focus typically on optimizing a unique criterion, usually the synthesis rate of a metabolite of interest or the rate of growth. Connectivity and non-linear regulatory effects, however, make it necessary to consider multiple objectives...

Descripción completa

Detalles Bibliográficos
Autores principales: Pozo, Carlos, Guillén-Gosálbez, Gonzalo, Sorribas, Albert, Jiménez, Laureano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447875/
https://www.ncbi.nlm.nih.gov/pubmed/23028457
http://dx.doi.org/10.1371/journal.pone.0043487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447875/
https://www.ncbi.nlm.nih.gov/pubmed/23028457
http://dx.doi.org/10.1371/journal.pone.0043487

Ejemplares similares