Dysregulated Toll-Like Receptor–Induced Interleukin-1β and Interleukin-6 Responses in Subjects at Risk for the Development of Type 1 Diabetes

We tested the hypothesis that altered Toll-like receptor (TLR) signaling may be involved in early stages of type 1 diabetes (T1D). To do so, we analyzed TLR-induced interleukin (IL)-1β and IL-6 responses in freshly isolated peripheral blood mononuclear cells (PBMNCs) from seropositive compared with...

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Detalles Bibliográficos
Autores principales: Alkanani, Aimon K., Rewers, Marian, Dong, Fran, Waugh, Kathleen, Gottlieb, Peter A., Zipris, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447890/
https://www.ncbi.nlm.nih.gov/pubmed/22751696
http://dx.doi.org/10.2337/db12-0099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447890/
https://www.ncbi.nlm.nih.gov/pubmed/22751696
http://dx.doi.org/10.2337/db12-0099

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