Doc2b Is a Key Effector of Insulin Secretion and Skeletal Muscle Insulin Sensitivity

Exocytosis of intracellular vesicles, such as insulin granules, is carried out by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Sec1/Munc18 (SM) proteins. An additional regulatory protein, Doc2b (double C2 domain), has recently been implicated in exocytosis from c...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramalingam, Latha, Oh, Eunjin, Yoder, Stephanie M., Brozinick, Joseph T., Kalwat, Michael A., Groffen, Alexander J., Verhage, Matthijs, Thurmond, Debbie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447898/
https://www.ncbi.nlm.nih.gov/pubmed/22698913
http://dx.doi.org/10.2337/db11-1525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447898/
https://www.ncbi.nlm.nih.gov/pubmed/22698913
http://dx.doi.org/10.2337/db11-1525

Ejemplares similares