Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy

Lipodystrophies are characterized by a loss of white adipose tissue, which causes ectopic lipid deposition, peripheral insulin resistance, reduced adipokine levels, and increased food intake (hyperphagia). The growth factor myostatin (MSTN) negatively regulates skeletal muscle growth, and mice with...

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Detalles Bibliográficos
Autores principales: Guo, Tingqing, Bond, Nichole D., Jou, William, Gavrilova, Oksana, Portas, Jennifer, McPherron, Alexandra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447905/
https://www.ncbi.nlm.nih.gov/pubmed/22596054
http://dx.doi.org/10.2337/db11-0915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447905/
https://www.ncbi.nlm.nih.gov/pubmed/22596054
http://dx.doi.org/10.2337/db11-0915

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