Diabetes-Impaired Wound Healing Is Improved by Matrix Therapy With Heparan Sulfate Glycosaminoglycan Mimetic OTR4120 in Rats

Wound healing in diabetes is frequently impaired, and its treatment remains a challenge. We tested a therapeutic strategy of potentiating intrinsic tissue regeneration by restoring the wound cellular environment using a heparan sulfate glycosaminoglycan mimetic, OTR4120. The effect of OTR4120 on hea...

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Detalles Bibliográficos
Autores principales: Tong, Miao, Tuk, Bastiaan, Shang, Peng, Hekking, Ineke M., Fijneman, Esther M.G., Guijt, Marnix, Hovius, Steven E.R., van Neck, Johan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447910/
https://www.ncbi.nlm.nih.gov/pubmed/22721969
http://dx.doi.org/10.2337/db11-1329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447910/
https://www.ncbi.nlm.nih.gov/pubmed/22721969
http://dx.doi.org/10.2337/db11-1329

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