Attenuated Pik3r1 Expression Prevents Insulin Resistance and Adipose Tissue Macrophage Accumulation in Diet-Induced Obese Mice

Obese white adipose tissue (AT) is characterized by large-scale infiltration of proinflammatory macrophages, in parallel with systemic insulin resistance; however, the cellular stimulus that initiates this signaling cascade and chemokine release is still unknown. The objective of this study was to d...

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Detalles Bibliográficos
Autores principales: McCurdy, Carrie E., Schenk, Simon, Holliday, Michael J., Philp, Andrew, Houck, Julie A., Patsouris, David, MacLean, Paul S., Majka, Susan M., Klemm, Dwight J., Friedman, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447911/
https://www.ncbi.nlm.nih.gov/pubmed/22698915
http://dx.doi.org/10.2337/db11-1433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447911/
https://www.ncbi.nlm.nih.gov/pubmed/22698915
http://dx.doi.org/10.2337/db11-1433

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