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In Vivo Imaging of Immuno-Spin Trapped Radicals With Molecular Magnetic Resonance Imaging in a Diabetic Mouse Model

Oxidative stress plays a major role in diabetes. In vivo levels of membrane-bound radicals (MBRs) in a streptozotocin-induced diabetic mouse model were uniquely detected by combining molecular magnetic resonance imaging (mMRI) and immunotrapping techniques. An anti-DMPO (5,5-dimethyl-1-pyrroline N-o...

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Detalles Bibliográficos
Autores principales: Towner, Rheal A., Smith, Nataliya, Saunders, Debra, Henderson, Michael, Downum, Kristen, Lupu, Florea, Silasi-Mansat, Robert, Ramirez, Dario C., Gomez-Mejiba, Sandra E., Bonini, Marcelo G., Ehrenshaft, Marilyn, Mason, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447912/
https://www.ncbi.nlm.nih.gov/pubmed/22698922
http://dx.doi.org/10.2337/db11-1540