In Vivo Inhibition of c-MYC in Myeloid Cells Impairs Tumor-Associated Macrophage Maturation and Pro-Tumoral Activities

Although tumor-associated macrophages (TAMs) are involved in tumor growth and metastasis, the mechanisms controlling their pro-tumoral activities remain largely unknown. The transcription factor c-MYC has been recently shown to regulate in vitro human macrophage polarization and be expressed in macr...

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Detalles Bibliográficos
Autores principales: Pello, Oscar M., Chèvre, Raphael, Laoui, Damya, De Juan, Alba, Lolo, Fidel, Andrés-Manzano, María Jesús, Serrano, Manuel, Van Ginderachter, Jo A., Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447925/
https://www.ncbi.nlm.nih.gov/pubmed/23028984
http://dx.doi.org/10.1371/journal.pone.0045399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447925/
https://www.ncbi.nlm.nih.gov/pubmed/23028984
http://dx.doi.org/10.1371/journal.pone.0045399

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