Defects in Mitochondrial Fission Protein Dynamin-Related Protein 1 Are Linked to Apoptotic Resistance and Autophagy in a Lung Cancer Model

Evasion of apoptosis is implicated in almost all aspects of cancer progression, as well as treatment resistance. In this study, resistance to apoptosis was identified in tumorigenic lung epithelial (A549) cells as a consequence of defects in mitochondrial and autophagic function. Mitochondrial funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomas, Kelly Jean, Jacobson, Marty R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447926/
https://www.ncbi.nlm.nih.gov/pubmed/23028930
http://dx.doi.org/10.1371/journal.pone.0045319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447926/
https://www.ncbi.nlm.nih.gov/pubmed/23028930
http://dx.doi.org/10.1371/journal.pone.0045319

Ejemplares similares