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Blocking of Connexin-Mediated Communication Promotes Neuroprotection during Acute Degeneration Induced by Mechanical Trauma

Accruing evidence indicates that connexin (Cx) channels in the gap junctions (GJ) are involved in neurodegeneration after injury. However, studies using KO animal models endowed apparently contradictory results in relation to the role of coupling in neuroprotection. We analyzed the role of Cx-mediat...

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Detalles Bibliográficos
Autores principales: Paschon, Vera, Higa, Guilherme Shigueto Vilar, Resende, Rodrigo Ribeiro, Britto, Luiz Roberto G., Kihara, Alexandre Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447938/
https://www.ncbi.nlm.nih.gov/pubmed/23029016
http://dx.doi.org/10.1371/journal.pone.0045449