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Blocking of Connexin-Mediated Communication Promotes Neuroprotection during Acute Degeneration Induced by Mechanical Trauma
Accruing evidence indicates that connexin (Cx) channels in the gap junctions (GJ) are involved in neurodegeneration after injury. However, studies using KO animal models endowed apparently contradictory results in relation to the role of coupling in neuroprotection. We analyzed the role of Cx-mediat...
Autores principales: | Paschon, Vera, Higa, Guilherme Shigueto Vilar, Resende, Rodrigo Ribeiro, Britto, Luiz Roberto G., Kihara, Alexandre Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447938/ https://www.ncbi.nlm.nih.gov/pubmed/23029016 http://dx.doi.org/10.1371/journal.pone.0045449 |
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