Cargando…

The p7 Protein of Hepatitis C Virus Forms Structurally Plastic, Minimalist Ion Channels

Hepatitis C virus (HCV) p7 is a membrane-associated oligomeric protein harboring ion channel activity. It is essential for effective assembly and release of infectious HCV particles and an attractive target for antiviral intervention. Yet, the self-assembly and molecular mechanism of p7 ion channell...

Descripción completa

Detalles Bibliográficos
Autores principales: Chandler, Danielle E., Penin, François, Schulten, Klaus, Chipot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447957/
https://www.ncbi.nlm.nih.gov/pubmed/23028296
http://dx.doi.org/10.1371/journal.pcbi.1002702