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The p7 Protein of Hepatitis C Virus Forms Structurally Plastic, Minimalist Ion Channels
Hepatitis C virus (HCV) p7 is a membrane-associated oligomeric protein harboring ion channel activity. It is essential for effective assembly and release of infectious HCV particles and an attractive target for antiviral intervention. Yet, the self-assembly and molecular mechanism of p7 ion channell...
Autores principales: | Chandler, Danielle E., Penin, François, Schulten, Klaus, Chipot, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447957/ https://www.ncbi.nlm.nih.gov/pubmed/23028296 http://dx.doi.org/10.1371/journal.pcbi.1002702 |
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