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Generation of Leishmania Hybrids by Whole Genomic DNA Transformation

Genetic exchange is a powerful tool to study gene function in microorganisms. Here, we tested the feasibility of generating Leishmania hybrids by electroporating genomic DNA of donor cells into recipient Leishmania parasites. The donor DNA was marked with a drug resistance marker facilitating the se...

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Detalles Bibliográficos
Autores principales: Coelho, Adriano C., Leprohon, Philippe, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447969/
https://www.ncbi.nlm.nih.gov/pubmed/23029579
http://dx.doi.org/10.1371/journal.pntd.0001817