High-Throughput 1,536-Well Fluorescence Polarization Assays for α(1)-Acid Glycoprotein and Human Serum Albumin Binding

Two major plasma proteins in humans are primarily responsible for drug binding, the α(1)-acid-glycoprotein (AGP) and human serum albumin (HSA). The availability of at least a semiquantitative high-throughput assay for assessment of protein binding is expected to aid in bridging the current gap betwe...

Descripción completa

Detalles Bibliográficos
Autores principales: Yasgar, Adam, Furdas, Silviya D., Maloney, David J., Jadhav, Ajit, Jung, Manfred, Simeonov, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447978/
https://www.ncbi.nlm.nih.gov/pubmed/23029124
http://dx.doi.org/10.1371/journal.pone.0045594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447978/
https://www.ncbi.nlm.nih.gov/pubmed/23029124
http://dx.doi.org/10.1371/journal.pone.0045594

Ejemplares similares