Inhibition of stromal CXCR4 impairs development of lung metastases

Compelling evidence has emerged in recent years indicating that stromal cells play a critical role in disease progression. CXCR4 is a G-protein-coupled receptor with a major role in lymphocyte homing. Its ligand, CXCL12, is a highly efficient chemotactic factor for T cells, monocytes, pre-B cells, d...

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Detalles Bibliográficos
Autores principales: D’Alterio, Crescenzo, Barbieri, Antonio, Portella, Luigi, Palma, Giuseppe, Polimeno, Marianeve, Riccio, Anna, Ieranò, Caterina, Franco, Renato, Scognamiglio, Giosuè, Bryce, Jane, Luciano, Antonio, Rea, Domenica, Arra, Claudio, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448054/
https://www.ncbi.nlm.nih.gov/pubmed/22399057
http://dx.doi.org/10.1007/s00262-012-1223-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448054/
https://www.ncbi.nlm.nih.gov/pubmed/22399057
http://dx.doi.org/10.1007/s00262-012-1223-7

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