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Genetic Control of Translesion Synthesis on Leading and Lagging DNA Strands in Plasmids Derived from Epstein-Barr Virus in Human Cells

DNA lesions in the template strand block synthesis by replicative DNA polymerases (Pols). Eukaryotic cells possess a number of specialized translesion synthesis (TLS) Pols with the ability to replicate through DNA lesions. The Epstein-Barr virus (EBV), a member of the herpesvirus family, infects hum...

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Detalles Bibliográficos
Autores principales: Yoon, Jung-Hoon, Prakash, Satya, Prakash, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448166/
https://www.ncbi.nlm.nih.gov/pubmed/22967980
http://dx.doi.org/10.1128/mBio.00271-12