Cargando…
Genetic Control of Translesion Synthesis on Leading and Lagging DNA Strands in Plasmids Derived from Epstein-Barr Virus in Human Cells
DNA lesions in the template strand block synthesis by replicative DNA polymerases (Pols). Eukaryotic cells possess a number of specialized translesion synthesis (TLS) Pols with the ability to replicate through DNA lesions. The Epstein-Barr virus (EBV), a member of the herpesvirus family, infects hum...
Autores principales: | Yoon, Jung-Hoon, Prakash, Satya, Prakash, Louise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448166/ https://www.ncbi.nlm.nih.gov/pubmed/22967980 http://dx.doi.org/10.1128/mBio.00271-12 |
Ejemplares similares
-
A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ
por: Yoon, Jung-Hoon, et al.
Publicado: (2021) -
DNA polymerase θ accomplishes translesion synthesis opposite 1,N(6)-ethenodeoxyadenosine with a remarkably high fidelity in human cells
por: Yoon, Jung-Hoon, et al.
Publicado: (2019) -
Structure and Mechanism of B-family DNA Polymerase ζ Specialized for Translesion DNA Synthesis
por: Malik, Radhika, et al.
Publicado: (2020) -
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
por: Malik, Radhika, et al.
Publicado: (2022) -
DNA polymerase ε leading strand signature mutations result from defects in its proofreading activity
por: Johnson, Robert E., et al.
Publicado: (2023)