Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice

BACKGROUND: Insulin resistance impairs nitric oxide (NO) bioavailability and obesity promotes a state of chronic inflammation and damages the vascular endothelium. Phosphodiesterase-5 inhibitors restore NO signaling and may reduce circulating inflammatory markers, and improve metabolic parameters th...

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Detalles Bibliográficos
Autores principales: Varma, Amit, Das, Anindita, Hoke, Nicholas N., Durrant, David E., Salloum, Fadi N., Kukreja, Rakesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448606/
https://www.ncbi.nlm.nih.gov/pubmed/23028874
http://dx.doi.org/10.1371/journal.pone.0045243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448606/
https://www.ncbi.nlm.nih.gov/pubmed/23028874
http://dx.doi.org/10.1371/journal.pone.0045243

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