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Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels

Gastrointestinal peristalsis is significantly dependent on the enteric nervous system. Constipation due to reduced peristalsis is a major side-effect of morphine, which limits the chronic usefulness of this excellent pain reliever in man. The ionic basis for the inhibition of enteric neuron excitabi...

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Detalles Bibliográficos
Autores principales: Smith, Tricia H., Grider, John R., Dewey, William L., Akbarali, Hamid I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448635/
https://www.ncbi.nlm.nih.gov/pubmed/23028881
http://dx.doi.org/10.1371/journal.pone.0045251