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Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels
Gastrointestinal peristalsis is significantly dependent on the enteric nervous system. Constipation due to reduced peristalsis is a major side-effect of morphine, which limits the chronic usefulness of this excellent pain reliever in man. The ionic basis for the inhibition of enteric neuron excitabi...
Autores principales: | Smith, Tricia H., Grider, John R., Dewey, William L., Akbarali, Hamid I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448635/ https://www.ncbi.nlm.nih.gov/pubmed/23028881 http://dx.doi.org/10.1371/journal.pone.0045251 |
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