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Functional Characterization of Newly-Discovered Mutations in Human SR-BI
In rodents, SR-BI has been firmly established as a physiologically relevant HDL receptor that mediates removal of HDL-cholesteryl esters (CE). However, its role in human lipoprotein metabolism is less defined. Recently, two unique point mutations in human SR-BI — S112F or T175A — were identified in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448639/ https://www.ncbi.nlm.nih.gov/pubmed/23029167 http://dx.doi.org/10.1371/journal.pone.0045660 |