The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms

The 2.2 Mb long dystrophin (DMD) gene, the largest gene in the human genome, corresponds to roughly 0.1% of the entire human DNA sequence. Mutations in this gene cause Duchenne muscular dystrophy and other milder X-linked, recessive dystrophinopathies. Using a custom-made tiling array, specifically...

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Detalles Bibliográficos
Autores principales: Bovolenta, Matteo, Erriquez, Daniela, Valli, Emanuele, Brioschi, Simona, Scotton, Chiara, Neri, Marcella, Falzarano, Maria Sofia, Gherardi, Samuele, Fabris, Marina, Rimessi, Paola, Gualandi, Francesca, Perini, Giovanni, Ferlini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448672/
https://www.ncbi.nlm.nih.gov/pubmed/23028937
http://dx.doi.org/10.1371/journal.pone.0045328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448672/
https://www.ncbi.nlm.nih.gov/pubmed/23028937
http://dx.doi.org/10.1371/journal.pone.0045328

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