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Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression

We aimed to assess whether pri-miRNA SNPs (miSNPs) could influence monocyte gene expression, either through marginal association or by interacting with polymorphisms located in 3'UTR regions (3utrSNPs). We then conducted a genome-wide search for marginal miSNPs effects and pairwise miSNPs × 3ut...

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Detalles Bibliográficos
Autores principales: Greliche, Nicolas, Zeller, Tanja, Wild, Philipp S., Rotival, Maxime, Schillert, Arne, Ziegler, Andreas, Deloukas, Panos, Erdmann, Jeanette, Hengstenberg, Christian, Ouwehand, Willem H., Samani, Nilesh J., Schunkert, Heribert, Munzel, Thomas, Lackner, Karl J., Cambien, François, Goodall, Alison H., Tiret, Laurence, Blankenberg, Stefan, Trégouët, David-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448685/
https://www.ncbi.nlm.nih.gov/pubmed/23029284
http://dx.doi.org/10.1371/journal.pone.0045863