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Associations between the Expression of Epigenetically Regulated Genes and the Expression of DNMTs and MBDs in Systemic Lupus Erythematosus

OBJECTIVES: We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status and the levels of three DNA methylation enzymes and two methyl CpG-binding domain (MBD) proteins. PATIENTS AND METHODS: CD4(+) T c...

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Detalles Bibliográficos
Autores principales: Balada, Eva, Castro-Marrero, Jesús, Felip, Lledó, Ordi-Ros, Josep, Vilardell-Tarrés, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448686/
https://www.ncbi.nlm.nih.gov/pubmed/23029299
http://dx.doi.org/10.1371/journal.pone.0045897