Age-Related Disease Association of Endogenous γ-H2AX Foci in Mononuclear Cells Derived from Leukapheresis

The phosphorylated form of histone H2AX (γ-H2AX) forms immunohistochemically detectable foci at DNA double strand breaks. In peripheral blood mononuclear cells (PBMCs) derived from leukapheresis from patients enrolled in the Baltimore Longitudinal Study of Aging, γ-H2AX foci increased in a linear fa...

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Detalles Bibliográficos
Autores principales: Schurman, Shepherd H., Dunn, Christopher A., Greaves, Rebecca, Yu, Binbing, Ferrucci, Luigi, Croteau, Deborah L., Seidman, Michael M., Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448703/
https://www.ncbi.nlm.nih.gov/pubmed/23029205
http://dx.doi.org/10.1371/journal.pone.0045728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448703/
https://www.ncbi.nlm.nih.gov/pubmed/23029205
http://dx.doi.org/10.1371/journal.pone.0045728

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