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Age-Related Disease Association of Endogenous γ-H2AX Foci in Mononuclear Cells Derived from Leukapheresis

The phosphorylated form of histone H2AX (γ-H2AX) forms immunohistochemically detectable foci at DNA double strand breaks. In peripheral blood mononuclear cells (PBMCs) derived from leukapheresis from patients enrolled in the Baltimore Longitudinal Study of Aging, γ-H2AX foci increased in a linear fa...

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Detalles Bibliográficos
Autores principales:	Schurman, Shepherd H., Dunn, Christopher A., Greaves, Rebecca, Yu, Binbing, Ferrucci, Luigi, Croteau, Deborah L., Seidman, Michael M., Bohr, Vilhelm A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448703/ https://www.ncbi.nlm.nih.gov/pubmed/23029205 http://dx.doi.org/10.1371/journal.pone.0045728

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