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MDM2 Expression Is Repressed by The RNA-Binding Protein RNPC1 via mRNA Stability
The RNA-binding protein RNPC1 is a target of the p53 family and forms a feedback regulatory loop with the p53 family proteins. The MDM2 oncogene, a key negative regulator of p53, plays a critical role in a variety of fundamental cellular processes. MDM2 expression is found to be regulated via gene a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449025/ https://www.ncbi.nlm.nih.gov/pubmed/22710720 http://dx.doi.org/10.1038/onc.2012.238 |