MDM2 Expression Is Repressed by The RNA-Binding Protein RNPC1 via mRNA Stability

The RNA-binding protein RNPC1 is a target of the p53 family and forms a feedback regulatory loop with the p53 family proteins. The MDM2 oncogene, a key negative regulator of p53, plays a critical role in a variety of fundamental cellular processes. MDM2 expression is found to be regulated via gene a...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Enshun, Zhang, Jin, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449025/
https://www.ncbi.nlm.nih.gov/pubmed/22710720
http://dx.doi.org/10.1038/onc.2012.238