PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38

PPM1D phosphatase, also called wild-type p53-induced phosphatase 1 (Wip1), promotes tumor development by inactivating the p53 tumor suppressor pathway. RBM38 RNA-binding protein, also called RNPC1 and a target of p53, inhibits p53 mRNA translation, which can be reversed by GSK3 protein kinase via ph...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Xu, Enshun, Zhang, Jin, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589422/
https://www.ncbi.nlm.nih.gov/pubmed/25823026
http://dx.doi.org/10.1038/onc.2015.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589422/
https://www.ncbi.nlm.nih.gov/pubmed/25823026
http://dx.doi.org/10.1038/onc.2015.31

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