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Reduced severity of peanut-induced anaphylaxis in TLR9-deficient mice is associated with selective defects in humoral immunity
Signaling through the innate immune system can promote or suppress allergic sensitization. TLR9 has modulatory effects on the mucosal immune system, and we hypothesized that TLR9 would influence susceptibility to allergic sensitization to foods. We observed that TLR9−/− mice were resistant to peanut...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449039/ https://www.ncbi.nlm.nih.gov/pubmed/22718261 http://dx.doi.org/10.1038/mi.2012.55 |