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Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E- selectin expression in human squamous cell carcinomas

Squamous cell carcinomas (SCC) are sun-induced skin cancers that are particularly numerous and aggressive in immunosuppressed individuals. SCC evade immune detection at least in part by down-regulating E-selectin on tumor vessels, thereby restricting entry of skin homing T cells into tumors. We find...

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Detalles Bibliográficos
Autores principales: Gehad, Ahmed, Lichtman, Michael, Schmults, Chrysalyne, Teague, Jessica E., Calarese, Adam, Jiang, Ying, Watanabe, Rei, Clark, Rachael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449043/
https://www.ncbi.nlm.nih.gov/pubmed/22718118
http://dx.doi.org/10.1038/jid.2012.190