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A High-Throughput Computational Framework for Identifying Significant Copy Number Aberrations from Array Comparative Genomic Hybridisation Data

Reliable identification of copy number aberrations (CNA) from comparative genomic hybridization data would be improved by the availability of a generalised method for processing large datasets. To this end, we developed swatCGH, a data analysis framework and region detection heuristic for computatio...

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Detalles Bibliográficos
Autores principales: Roberts, Ian, Carter, Stephanie A., Scarpini, Cinzia G., Karagavriilidou, Konstantina, Barna, Jenny C. J., Calleja, Mark, Coleman, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449101/
https://www.ncbi.nlm.nih.gov/pubmed/23008709
http://dx.doi.org/10.1155/2012/876976