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Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications

AKT1 controls important processes in medial temporal lobe (MTL) development and plasticity, but the impact of human genetic variation in AKT1 on these processes is not known in healthy or disease states. Here, we report that an AKT1 variant (rs1130233) previously associated with AKT1 protein express...

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Detalles Bibliográficos
Autores principales: Tan, H Y, Chen, A G, Chen, Q, Browne, L B, Verchinski, B, Kolachana, B, Zhang, F, Apud, J, Callicott, J H, Mattay, V S, Weinberger, D R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449232/
https://www.ncbi.nlm.nih.gov/pubmed/21788944
http://dx.doi.org/10.1038/mp.2011.91