Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans

Iron-catalyzed generation of free radicals leads to molecular damage in vivo, and has been proposed to contribute to organismal ageing. Here we investigate the role of free iron in ageing in the nematode Caenorhabditis elegans. Media supplementation with Fe(III) increased free iron levels in vivo, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Valentini, Sara, Cabreiro, Filipe, Ackerman, Daniel, Alam, Muhammed M., Kunze, Micha B.A., Kay, Christopher W.M., Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449239/
https://www.ncbi.nlm.nih.gov/pubmed/22445852
http://dx.doi.org/10.1016/j.mad.2012.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449239/
https://www.ncbi.nlm.nih.gov/pubmed/22445852
http://dx.doi.org/10.1016/j.mad.2012.03.003

Ejemplares similares