Cargando…

Nilotinib based pharmacophore models for BCRABL

Tyrosine kinase inhibitors have revolutionized the treatment of several malignancies, converting lethal diseases in a manageable aspect. Imitanib, a small molecule ABL kinase inhibitor is a highly effective therapy for early phase chronic myeloid leukemia (CML), which has constitutively active ABL k...

Descripción completa

Detalles Bibliográficos
Autor principal: Sabitha, Kesavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449370/
https://www.ncbi.nlm.nih.gov/pubmed/23055606
http://dx.doi.org/10.6026/97320630008658