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Structure based virtual screening of inhibitors for binding at the allosteric site of HCV RNA dependent RNA polymerase

Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality. There is no effective treatment or prevention till date for HCV infection. We describe the computed bin...

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Detalles Bibliográficos
Autores principales: Revikumar, Amjesh, Nair, Achuthsankar Sukumaran, Sundaram, Sugunan Vetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449378/
https://www.ncbi.nlm.nih.gov/pubmed/23055616
http://dx.doi.org/10.6026/97320630008716