Production of high titre disabled infectious single cycle (DISC) HSV from a microcarrier culture

Disabled Infectious Single Cycle (DISC) HSV-2 has been cultured in the complimentary cell line CR2 to provide high titre bulk material suitable for the purification of the virus as a live viral vaccine. CR2 cells are cultured on the microcarrier Cytodex-1 at 5 g l-1 in small scale (1 l) and larger s...

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Detalles Bibliográficos
Autores principales: Zecchini, T.A., Smith, R.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449936/
https://www.ncbi.nlm.nih.gov/pubmed/19003370
http://dx.doi.org/10.1023/A:1008005200711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449936/
https://www.ncbi.nlm.nih.gov/pubmed/19003370
http://dx.doi.org/10.1023/A:1008005200711

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