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Production of high titre disabled infectious single cycle (DISC) HSV from a microcarrier culture
Disabled Infectious Single Cycle (DISC) HSV-2 has been cultured in the complimentary cell line CR2 to provide high titre bulk material suitable for the purification of the virus as a live viral vaccine. CR2 cells are cultured on the microcarrier Cytodex-1 at 5 g l-1 in small scale (1 l) and larger s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Kluwer Academic Publishers
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449936/ https://www.ncbi.nlm.nih.gov/pubmed/19003370 http://dx.doi.org/10.1023/A:1008005200711 |