Does sumatriptan cross the blood–brain barrier in animals and man?

Sumatriptan, a relatively hydrophilic triptan, based on several animal studies has been regarded to be unable to cross the blood–brain barrier (BBB). In more recent animal studies there are strong indications that sumatriptan to some extent can cross the BBB. The CNS adverse events of sumatriptan in...

Descripción completa

Detalles Bibliográficos
Autor principal: Tfelt-Hansen, Peer Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452191/
https://www.ncbi.nlm.nih.gov/pubmed/20012125
http://dx.doi.org/10.1007/s10194-009-0170-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3452191/
https://www.ncbi.nlm.nih.gov/pubmed/20012125
http://dx.doi.org/10.1007/s10194-009-0170-y

Ejemplares similares