Compound C Prevents the Unfolded Protein Response during Glucose Deprivation through a Mechanism Independent of AMPK and BMP Signaling

Inhibiting the unfolded protein response (UPR) can be a therapeutic approach, especially for targeting the tumor microenvironment. Here, we show that compound C (also known as dorsomorphin), a small-molecule inhibitor of AMP-activated protein kinase (AMPK) and bone morphogenetic protein (BMP) signal...

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Detalles Bibliográficos
Autores principales: Saito, Sakae, Furuno, Aki, Sakurai, Junko, Park, Hae-Ryong, Shin-ya, Kazuo, Tomida, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454318/
https://www.ncbi.nlm.nih.gov/pubmed/23029271
http://dx.doi.org/10.1371/journal.pone.0045845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454318/
https://www.ncbi.nlm.nih.gov/pubmed/23029271
http://dx.doi.org/10.1371/journal.pone.0045845

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