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Discovery and Characterization of Human Exonic Transcriptional Regulatory Elements

We sought exonic transcriptional regulatory elements by shotgun cloning human cDNA fragments into luciferase reporter vectors and measuring the resulting expression levels in liver cells. We uncovered seven regulatory elements within coding regions and three within 3' untranslated regions (UTRs...

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Detalles Bibliográficos
Autores principales: Khan, Arshad H., Lin, Andy, Smith, Desmond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454335/
https://www.ncbi.nlm.nih.gov/pubmed/23029400
http://dx.doi.org/10.1371/journal.pone.0046098