Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin

It has been reported that the expression and activity of the interferon-inducible, dsRNA-dependent protein kinase, PKR, is increased in mammary carcinoma cell lines and primary tumor samples. To extend these findings and determine how PKR signaling may affect breast cancer cell sensitivity to chemot...

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Detalles Bibliográficos
Autores principales: Bennett, Richard L., Carruthers, Aubrey L., Hui, Teng, Kerney, Krystal R., Liu, Xiangfei, May, W. Stratford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454339/
https://www.ncbi.nlm.nih.gov/pubmed/23029376
http://dx.doi.org/10.1371/journal.pone.0046040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454339/
https://www.ncbi.nlm.nih.gov/pubmed/23029376
http://dx.doi.org/10.1371/journal.pone.0046040

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